Sulfo-dibenzocyclooctyne-biotin conjugate

ALDRICH/760706 - for Copper-free Click Chemistry

Synonym: Sulfo-DBCO-biotin

Empirical Formula (Hill Notation): C₃₇H₅₀N₆O₇S₂
Molecular Weight: 754.96
Linear Formula: C₃₇H₅₀N₆O₇S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-760706-5MG	5 mg	$123.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

form	solid
InChI	1S/C31H35N5O7S2.C6H15N/c37-27(12-6-5-11-25-29-23(19-44-25)34-31(40)35-29)33-17-26(45(41,42)43)30(39)32-16-15-28(38)36-18-22-9-2-1-7-20(22)13-14-21-8-3-4-10-24(21)36;1-4-7(5-2)6-3/h1-4,7-10,23,25-26,29H,5-6,11-12,15-19H2,(H,32,39)(H,33,37)(H2,34,35,40)(H,41,42,43);4-6H2,1-3H3/t23-,25-,26?,29-;/m0./s1
InChI key	RACLEVCKGUBCTH-GESOYTMLSA-N
reaction suitability	reaction type: click chemistry
	reagent type: cross-linking reagent
SMILES string	CC[NH+](CC)CC.[O-]S(=O)(=O)C(CNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)C(=O)NCCC(=O)N3Cc4ccccc4C#Cc5ccccc35
storage temp.	−20°C

Application:	Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002 )
Features and Benefits:	More efficient labeling will occur at higher temperatures and with greater excess of biotin reagent. Typical reaction times are up to 4 hours, but longer incubation periods should be used if concentration is low or if low labeling is observed. Product is most efficient when first dissolved in a water miscible organic solvent and then diluted in aqueous reaction buffer when needed. Stock solutions in DMSO have been shown to be stable in the freezer for up to 3 months.
General description:	This sulfonated azadibenzocyclooctyne-biotin derivative is a highly water soluble and versatile biotinylation reagent for labeling azide containing molecules or compounds. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions.This dibenzocyclooctyne will react with azide-functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage. Subsequent labeled molecules can be purified using streptavidin or avidin affinity reagents.
Packaging:	5 mg in amber glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	12352200

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