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Azide-PEG3-biotin conjugate

ALDRICH/762024

Synonym: Polyethylene glycol; N-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl]hexahydro-2-oxo-(3aS,4S,6aR)- 1H-thieno[3,4-d ]imidazole-4-pentanamide; Biotin-PEG3-azide

CAS Number: 875770-34-6
Empirical Formula (Hill Notation): C18H32N6O5S
Molecular Weight: 444.55
MDL Number: MFCD20134145
Linear Formula: C18H32N6O5S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-762024-10MG 10 mg
 $81.10
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45-762024-25MG 25 mg
 $162.00
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45-762024-100MG 100 mg
 $350.00
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form solid
InChI 1S/C18H32N6O5S/c19-24-21-6-8-28-10-12-29-11-9-27-7-5-20-16(25)4-2-1-3-15-17-14(13-30-15)22-18(26)23-17/h14-15,17H,1-13H2,(H,20,25)(H2,22,23,26)/t14-,15-,17-/m1/s1
InChI key ZWFOOMQCYIGZBE-BFYDXBDKSA-N
Quality Level 200 
reaction suitability reaction type: click chemistry
SMILES string O=C1N[C@](CS[C@H]2CCCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)([H])[C@]2([H])N1
storage temp. −20°C
Application: Azide-PEG3-biotin conjugate has been used for the detection of a cellular alkyne cholesterol analog via click chemistry using fluorescence microscopy after incubation with a fluorescent streptavidin-conjugate. It has also been used to prepare a novel multifunctional benzophenone linker that can be used for pull-down assays, photoaffinity labeling and double-click stapling techniques.
Application: Biotinylation reagent for labeling alkyne containing molecules or biomolecules using either copper-catalyzed 1,3 dipolar cycloaddition click chemistry or copper-free click chemistry with cyclooctyne derivatives. The azide group reacts with alkynes to form a stable triazole linkage facilitating the introduction of biotin into your alkyne modified system of interest. This reaction is bioorthogonal or in other words compatible with biological systems in that it′s components do not react with the biological environment.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002 )
Packaging: 10, 25, 100 mg in clear glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352125

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