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DL-α-Tocopherol methoxypolyethylene glycol succinate

ALDRICH/763896

Synonym: Polyethylene glycol; TPGS-750-M

CAS Number: 1309573-60-1
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-763896-1G 1 g
$52.80
1/EA
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45-763896-10G 10 g
$358.00
1/EA
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45-763896-25G 25 g
$704.00
1/EA
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45-763896-100G 100 g
$1390.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 763896-25G
12 Principles of Green Chemistry: Principle 9—Catalytic reagents (as selective as possible) are superior to stoichiometric reagents.

 

form powder
greener alternative category  , Aligned 
greener alternative product characteristics Catalysis
Learn more about the Principles of Green Chemistry .
Quality Level 100 
reaction suitability reagent type: catalyst
reaction type: C-H Activation
  reagent type: surfactant
sustainability Greener Alternative Product
transition temp Tm 29-34
Application: On the Way Towards Greener Transition-Metal-Catalyzed Processes as Quantified by E Factors 
Application: DL-α-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M), a biodegradable and water-soluble derivative of natural vitamin E, is used as an environmentally benign nonionic surfactant in metal-catalyzed cross-coupling reactions in water. It is used in Heck, Suzuki-Miyaura, Sonogashira, and Negishi like couplings reactions. It can also be utilized in aminations, C-H activations, and olefin metathesis reactions.
TPGS-750-M can also be employed in:
•  The nucleophilic aromatic substitution reaction of aryl and heteroaryl halides with nitrogen, oxygen, and sulfur nucleophiles under mild conditions.
•  The preparation of quinoxaline-2,3 diones from quinoxalinones via C(sp2)-H hydroxylation reaction.
•  The intramolecular N-arylation of amines using a copper catalyst.

General description: Learn More at the Professor and Product Portal  of Professor Bruce Lipshutz.
General description: We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product TPGS-750-M is a lead surfactant for many transition metal-catalyzed cross-couplings and has been enhanced for catalytic efficiency. Find details here .
Other Notes: Watch Professor Lipshutz talk about TPGS-750-M in this webinar:
From milligrams to kilograms: synthetic chemistry following nature′s lead 
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 51171641

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