Synonym: 3,6,9,12-Tetraoxapentadec-14-yn-1-amine; Acetylene-PEG4-amine; H2N-PEG4-propyne; Triethylene glycol 2-aminoethyl propargyl ether
CAS Number: 1013921-36-2
Empirical Formula (Hill Notation): C11H21NO4
Molecular Weight: 231.29
MDL Number: MFCD22380736
Linear Formula: C11H21NO4
Product Type: Chemical
| form |
liquid |
| functional group |
alkyne |
| |
amine |
| InChI |
1S/C11H21NO4/c1-2-4-13-6-8-15-10-11-16-9-7-14-5-3-12/h1H,3-12H2 |
| InChI key |
QDLPAHLHHBCWOW-UHFFFAOYSA-N |
| reaction suitability |
reaction type: click chemistry |
| |
reagent type: cross-linking reagent |
| SMILES string |
NCCOCCOCCOCCOCC#C |
| storage temp. |
−20°C |
| Application: |
Heterobifunctional linker enabling the connection of an azide containing compound or biomolecule to one with a carboxylic acid. The amine group can be linked to a carboxylic acid through standard coupling procedures (EDC, product #39391, etc...) and the terminal alkyne will react with azides via copper-catalyzed 1,3-dipolar cycloaddition click chemistry. The hydrophilic PEG spacer adds to the water solubility of this reagent, allowing for easy modification of carboxylic acid containing biomolecules such as antibodies, proteins and peptides with the terminal alkyne. The PEG spacer also reduces aggregation of modified proteins stored in solution by adding hydrophilic character. |
| Application: |
Amino-PEG4-alkyne may be used to synthesize alkynyl-functionalized iron oxide nanoparticles (IONPs) for preparing glycopolymer-based iron oxide nanoparticles (GIONs) for potential bioscience applications. |
| Packaging: |
10 mg in clear glass bottle |
| Packaging: |
25 mg in amber glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Storage Temp. |
−20°C |
| UNSPSC |
12352106 |
