Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)
ALDRICH/764779 - PEG average Mn 2,000, PDLLA average Mn 2,000
Synonym: PEG-PDLLA
Product Type: Chemical
| degradation timeframe | 2-4 weeks |
| description | n=45, m=28 (typical) |
| typical PEG PDI<1.1; overall PDI<1.4 (THF, PEO) | |
| form | pellets |
| mol wt | average Mn 4,000 (total) |
| PDLLA average Mn 2,000 | |
| PEG average Mn 2,000 | |
| PDI | ≤1.4 |
| storage temp. | 2-8°C |
| transition temp | Tg 11 °C (PEG block) |
| Tg 88 °C (PDLLA block) | |
| Tm 244-248 °C |
| Application: | Used as a carrier for the controlled and targeted release of anticancer hydrophobic drugs. |
| Application: | water-solubilization of drugs |
| Features and Benefits: | • Good biocompatibility, low immunogenicity and good degradability. • Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application. |
| General description: | Block copolymer micelles are widely used in drug delivery applications. PEG-PDLLA is a biodegradable polymeric micelle which is used as carriers for hydrophobic drugs like paclitaxel. PEG is the hydrophilic part and PDLLA is the hydrophobic part which forms the micelle core wherein the hydrophobic drug is loaded. |
| Packaging: | 1 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12162002 |