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(S)-2-Aminobutane-1,4-dithiol hydrochloride

ALDRICH/774405 - 99% (titration)

Synonym: (S)-2-Aminobutane-1,4-dithiol hydrochloride; (2S)-2-Amino-1,4-dimercaptobutane hydrochloride; DTBA; Dithiobutylamine

CAS Number: 1363376-98-0
Empirical Formula (Hill Notation): C4H11NS2 · HCl
Molecular Weight: 173.73
MDL Number: MFCD23704430
Linear Formula: C4H11NS2 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-774405-1G 1 g
 $202.00
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assay 99% (titration)
form solid
InChI 1S/C4H11NS2.ClH/c5-4(3-7)1-2-6;/h4,6-7H,1-3,5H2;1H/t4-;/m0./s1
InChI key HWWPXJZINVJNBM-WCCKRBBISA-N
mp 210-225 °C
reaction suitability reagent type: reductant
SMILES string Cl.N[C@H](CS)CCS
storage temp. 2-8°C
Application: (S)-2-Aminobutane-1,4-dithiol hydrochloride (DTBA), also known as dithiobutylamine, is a biological reducing reagent with enhanced properties over other commonly used reagents. DTBA was shown to reduce small molecule disulfides 3-5x faster than DTT and was able to reduce (activate) the cysteine dependent protease papain 14x faster than DTT. In addition, due to the presence of the primary amine group, removal of DTBA from mixtures after use is simplified and can be achieved using cation exchange resin.
Application: Dithiobutylamine or DTBA is a new biological reducing reagent with enhanced properties over other commonly used reagents. DTBA was shown to reduce small molecule disulfides 3-5x faster than DTT and was able to reduce (activate) the cysteine dependent protease papain 14x faster than DTT. In addition, due to the presence of the primary amine group, removal of DTBA from mixtures after use is simplified and can be achieved using cation exchange resin.
Packaging: 1, 5 g in glass bottle
Packaging: 25 g in poly bottle
Purity 99% (titration)
mp 210-225 °C
Storage Temp. 2-8°C
UNSPSC 12352200

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