Synonym: 2,5-Dioxopyrrolidin-1-yl 2-(bicyclo[2.2.1]hept-5-en-2-yl)acetate; 5-Norbornene-2-acetic acid NHS; Bicyclo[2.2.1]hept-5-ene-2-acetic acid N-hydroxysuccinimide ester; Bicyclo[2.2.1]hept-5-ene-2-acetic acid, 2,5-dioxo-1-pyrrolidinyl ester
CAS Number: 1234203-45-2
Empirical Formula (Hill Notation): C13H15NO4
Molecular Weight: 249.26
Linear Formula: C13H15NO4
Product Type: Chemical
| assay |
97% |
| form |
solid |
| functional group |
NHS ester |
| InChI |
1S/C13H15NO4/c15-11-3-4-12(16)14(11)18-13(17)7-10-6-8-1-2-9(10)5-8/h1-2,8-10H,3-7H2 |
| InChI key |
AOGNOQQTUYLDKN-UHFFFAOYSA-N |
| mp |
115-120 °C |
| Quality Level |
100  |
| reaction suitability |
reaction type: click chemistry |
| |
reagent type: linker |
| SMILES string |
O=C(N1OC(C[C@H]2[C@@H]3C=C[C@@H](C3)C2)=O)CCC1=O |
| storage temp. |
2-8°C |
| Application: |
Succinimidyl ester functionalized norbornene. Succinimidyl ester group will react with amine containing compounds such as lysine residues on proteins/peptides. Norbornene has been shown to react with 1; 2; 4; 5-tetrazines in an inverse electron demand Diels-Alder cycloaddition reaction which is a bioorthogonal reaction demonstrated to be useful in biological imaging applications. |
| Packaging: |
25, 100 mg in amber glass bottle |
| Symbol |
 GHS07 |
| Signal word |
Warning |
| Hazard statements |
H302 |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
97% |
| mp |
115-120 °C |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352106 |
