SPhos Pd G3
ALDRICH/776246 - 97%
Synonym: (2-
CAS Number: 1445085-82-4
Empirical Formula (Hill Notation): C39H48NO5PPdS
Molecular Weight: 780.26
Linear Formula: C39H48NO5PPdS
Product Type: Chemical
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 776246-5G
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 776246-1G
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 776246-250MG
assay | 97% |
feature | generation 3 |
form | solid |
functional group | phosphine |
InChI | 1S/C26H35O2P.C12H10N.CH4O |
InChI key | SCWODMZBSVVMRH-UHFFFAOYSA |
mp | 197-214 °C |
Quality Level | 100 ![]() |
reaction suitability | core: palladium |
reaction type: Buchwald-Hartwig Cross Coupling Reaction | |
reaction type: Heck Reaction | |
reaction type: Hiyama Coupling | |
reaction type: Negishi Coupling | |
reaction type: Sonogashira Coupling | |
reaction type: Stille Coupling | |
reaction type: Suzuki-Miyaura Coupling | |
reagent type: catalyst reaction type: Cross Couplings |
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SMILES string | CS(=O)(=O)O[Pd]c1ccccc1-c |
storage temp. | 2-8°C |
Application: | Pd catalyst for cross-coupling |
Application: | SPhos Pd G3 can be used as a precatalyst in the Suzuki–Miyaura catalyst–transfer polymerization (SCTP) reaction of a wide spectrum of monomers, including electron-rich to electron-deficient (hetero)arenes. It is also used as a catalyst in the formation of a Csp3–Csp2 bond between sterically hindered boronic hemiester and quinone diazide, which is the key intermediate step in the enantioselective synthesis of azamerone. |
General description: | SPhos Pd G3 is a third-generation (G3) Buchwald precatalyst that can be used in cross-coupling reactions for the formation of C-C, C-N, C-O, C-F, C-CF3, and C-S bonds. It is air-, moisture-, and thermally stable and is highly soluble in a wide range of common organic solvents. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species, and accurate control of ligand: palladium ratio. |
Packaging: | 1, 5, 25 g in glass bottle |
Packaging: | 250 mg in glass bottle |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 97% |
mp | 197-214 °C |
Storage Temp. | 2-8°C |
UNSPSC | 12161600 |