K-Oxyma
ALDRICH/776874 - 97%
Synonym: 2-
CAS Number: 158014-03-0
Empirical Formula (Hill Notation): C5H5KN2O3
Molecular Weight: 180.20
MDL Number: MFCD26960809
Linear Formula: C5H5KN2O3
Product Type: Chemical
application(s) | peptide synthesis |
assay | 97% |
form | powder |
InChI | 1S/C5H6N2O3.K/c1-2-10-5(8 |
InChI key | ZFBMUWGNRJITLS-KQGICBIGSA |
mp | 141-147 |
reaction suitability | reaction type: Addition Reactions |
SMILES string | CCOC(/C(C#N)=N/[O-])=O.[K |
storage temp. | 2-8°C |
Application: | • Non-explosive replacement for HOBt and HOAt with at least comparable performance to HOAt • Outperforms HOAt in sterically demanding peptide bond formations • Compatible with carbodiimide-mediated; solution and solid phase peptide coupling; • Less epimerization than HOBt in fragment condensation reactions • K-salt especially useful in peptide coupling on mild acid-labile resins such as 2-chlorotrityl; leading to minimal to no cleavage of the peptide from the resin due to its more alkaline character • K-salt has a higher melting point than OxymaPure |
Packaging: | 50, 250 g in glass bottle |
Hazard Codes | T |
Risk Statements | 20/21-25-43 |
Safety Statements | 36/37-45 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 97% |
mp | 141-147 |
Storage Temp. | 2-8°C |
UNSPSC | 12352111 |