Garg 4,5-indolyne precursor
ALDRICH/795569 - 95%
Synonym: 4-(Trimethylsilyl)-1H-indol-5-yl trifluoromethanesulfonate
CAS Number: 1259448-37-7
Empirical Formula (Hill Notation): C12H14F3NO3SSi
Molecular Weight: 337.39
MDL Number: MFCD25976536
Linear Formula: C12H14F3NO3SSi
Product Type: Chemical
| assay | 95% |
| form | solid |
| functional group | fluoro |
| triflate | |
| InChI | 1S/C12H14F3NO3SSi/c1-21(2 |
| InChI key | LLCJFYYASDIOJN-UHFFFAOYSA |
| mp | 43-48 °C |
| Quality Level | 100  |
| SMILES string | O=S(OC1=C([Si](C)(C)C)C2= |
| storage temp. | 2-8°C |
| Application: | Indolyne precursor can be activated under mild fluoride conditions, which are highly reactive with dienes and other dipolariphiles (e.g. azides) to provide cycloaddition products containing an indole motif. |
| General description: | Garg 4,5-indolyne precursor is an indolyne precursor developed by Professor Neil Garg and coworkers. It is widely used for the synthesis of various N-heterocyclic based compounds. It is also useful for the preparation of substituted indoles (Diels–Alder and azide cycloaddition products). |
| Other Notes: | Indolyne Experimental and Computational Studies: Synthetic Applications and Origins of Selectivities of Nucleophilic Additions  |
| Other Notes: | Regioselective reactions of 3; 4-pyridynes enabled by the aryne distortion model |
| Packaging: | 1, 100 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 95% |
| mp | 43-48 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352100 |