SnAP 3-Spiro-(4-Pip) M Reagent

ALDRICH/804142

Synonym: tert-butyl 4-amino-4-(((tributylstannyl)methoxy)methyl) piperidine-1-carboxylate

Empirical Formula (Hill Notation): C₂₄H₅₀N₂O₃Sn
Molecular Weight: 533.38
MDL Number: MFCD29905051
Linear Formula: C₂₄H₅₀N₂O₃Sn
Product Type: Chemical

SnAP Ring Orientation

form	liquid
functional group	ether
InChI	1S/C12H23N2O3.3C4H9.Sn/c1-11(2,3)17-10(15)14-7-5-12(13,6-8-14)9-16-4;31-3-4-2;/h4-9,13H2,1-3H3;31,3-4H2,2H3;
InChI key	XZUSOLFDFJLEMZ-UHFFFAOYSA-N
Quality Level	100
SMILES string	CCCC[Sn](CCCC)(COCC1(CCN(C(OC(C)(C)C)=O)CC1)N)CCCC
storage temp.	−20°C

Application:	SnAP Reagents provide a one-step route, in tandem with various aldehyde substrates, to saturated N-heterocycles. The synthesis of N-heterocycles through SnAP Reagents requires mild reaction conditions, and aldehydes bearing aryl, heteroaryl, glyoxyl, aliphatic, and halogenated groups are well tolerated. This product was introduced in collaboration with the Bode Research Group
Application:	SnAP 3-Spiro-(4-Pip) M Reagent may be used in the preparation of unprotected, saturated N-heterocyclic compounds. Automate your N-heterocycle formation with Synple Automated Synthesis Platform (SYNPLE-SC002 )
General description:	SnAP (Sn amino protocol) reagents have been developed by Professor Dr. Jeffrey Bode and co-workers. (These reagents are useful for the preparation of medium-ring (6-9 membered) saturated N-heterocycles, including bicyclic and spirocyclic structures.) SnAP reagents are stable and easy to handle in laboratories. They can be prepared from simple raw materials.
Other Notes:	Technology spotlight: SnAP Reagents Professor product portal: Jeffrey Bode Research Group SnAP Reagents for the Synthesis of Piperazines and Morpholines SnAP reagents for the one-step synthesis of medium-ring saturated N-heterocycles from aldehydes SnAP Reagents for a Cross-Coupling Approach to the One-Step Synthesis of Saturated N-Heterocycles Bespoke SnAP Reagents for the Synthesis of C-Substituted Spirocyclic and Bicyclic Saturated N-Heterocycles
Packaging:	500 mg in glass bottle

Storage Temp.	−20°C
UNSPSC	12352103