SnAP 2-Spiro-(2-Pyr) M Reagent

ALDRICH/804185

Synonym: tert-butyl 3-(aminomethyl)-3-((tributylstannyl)methoxy) pyrrolidine-1-carboxylate

Empirical Formula (Hill Notation): C₂₃H₄₈N₂O₃Sn
Molecular Weight: 519.35
MDL Number: MFCD29049344
Linear Formula: C₂₃H₄₈N₂O₃Sn
Product Type: Chemical

SnAP Ring Orientation

density	1.143 at 25 °C
description	Fp >230°F
form	powder
InChI	1S/C11H21N2O3.3C4H9.Sn/c1-10(2,3)16-9(14)13-6-5-11(7-12,8-13)15-4;31-3-4-2;/h4-8,12H2,1-3H3;31,3-4H2,2H3;
InChI key	FITIMZOFKJTPHZ-UHFFFAOYSA-N
mp	235 °C
Quality Level	100
SMILES string	CCCC[Sn](CCCC)(COC1(CN(C(OC(C)(C)C)=O)CC1)CN)CCCC
storage temp.	−20°C

Application:	SnAP Reagents provide a one-step route, in tandem with various aldehyde substrates, to saturated N-heterocycles. The synthesis of N-heterocycles through SnAP Reagents requires mild reaction conditions, and aldehydes bearing aryl, heteroaryl, glyoxyl, aliphatic, and halogenated groups are well tolerated. This product was introduced in collaboration with the Bode Research Group Automate your N-heterocycle formation with Synple Automated Synthesis Platform (SYNPLE-SC002 )
Other Notes:	Technology spotlight: SnAP Reagents Professor product portal: Jeffrey Bode Research Group SnAP Reagents for the Synthesis of Piperazines and Morpholines SnAP reagents for the one-step synthesis of medium-ring saturated N-heterocycles from aldehydes SnAP Reagents for a Cross-Coupling Approach to the One-Step Synthesis of Saturated N-Heterocycles Bespoke SnAP Reagents for the Synthesis of C-Substituted Spirocyclic and Bicyclic Saturated N-Heterocycles
Packaging:	500 mg in glass bottle