N⁶-Propargyl-ATP sodium salt

ALDRICH/808490

Synonym: (N⁶pATP) sodium salt; N⁶-Propargyl-adenosine-5’-triphosphate sodium salt

Empirical Formula (Hill Notation): C₁₃H₁₈N₅O₁₃P₃ · xNa⁺
Molecular Weight: 545.23 (free acid basis)
Linear Formula: C₁₃H₁₈N₅O₁₃P₃ · xNa⁺
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-808490-1MG	1 mg	$422.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95% (HPLC)
form	solid
InChI	1S/C13H18N5O13P3/c1-2-3-14-11-8-12(16-5-15-11)18(6-17-8)13-10(20)9(19)7(29-13)4-28-33(24,25)31-34(26,27)30-32(21,22)23/h1,5-7,9-10,13,19-20H,3-4H2,(H,24,25)(H,26,27)(H,14,15,16)(H2,21,22,23)/t7-,9-,10-,13?/m1/s1
InChI key	MUOIWXPACQCYQC-RJNFYWFKSA-N
Quality Level	200
reaction suitability	reaction type: click chemistry
shipped in	wet ice
SMILES string	O[C@@H]([C@H]1O)[C@@H](COP(O)(OP(O)(OP(O)(O)=O)=O)=O)O[C@@H]1N2C=NC3=C2N=CN=C3NCC#C
solubility	10 mM Tris-HCl, pH 7.5: soluble
storage temp.	−20°C

Application:

N⁶-Propargyl-ATP is suitable for in vitro AMPylation of proteins as well as in vitro polyadenylation of RNA. The resulting alkyne-functionalized protein or RNA can be processed using Cu(I)-catalyzed click chemistry to attach azide-labeled molecules. This gives options such as introduction of a biotin group for purification tasks, introduction of a fluorescent group for detection, or crosslinking to other azide-functionalized biomolecules.

Packaging:

1 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352106

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