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γ-[(6-Azidohexyl)-imido]-ATP sodium salt

ALDRICH/808520

Synonym: γ-[(6-Azidohexyl)-imido]-adenosine-5’-triphosphate sodium salt

Empirical Formula (Hill Notation): C16H28N9O12P3 · xNa+
Molecular Weight: 631.37 (free acid basis)
Linear Formula: C16H28N9O12P3 · xNa+
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-808520-1MG 1 mg
 $475.00
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assay ≥95% (HPLC)
form powder
InChI 1S/C16H28N9O12P3/c17-14-11-15(20-8-19-14)25(9-21-11)16-13(27)12(26)10(35-16)7-34-39(30,31)37-40(32,33)36-38(28,29)23-6-4-2-1-3-5-22-24-18/h8-10,12-13,16,26-27H,1-7H2,(H,30,31)(H,32,33)(H2,17,19,20)(H2,23,28,29)/t10-,12-,13-,16?/m1/s1
InChI key FZLLGYSKHRTLRX-AARXTDBFSA-N
Quality Level 200 
reaction suitability reaction type: click chemistry
shipped in wet ice
SMILES string O[C@@H]([C@H]1O)[C@@H](COP(O)(OP(O)(OP(NCCCCCCN=[N+]=[N-])(O)=O)=O)=O)O[C@@H]1N2C=NC3=C2N=CN=C3N
solubility 10 mM Tris-HCl, pH 7.5: soluble
storage temp. −20°C
Application: Lee, et al., reported a non-radioactive version of in vitro phosphorylation where γ-[(6-Azidohexyl)-imido]-ATP (compound 6) was successfully used instead of γ-32P-modified ATP to phosphorylate GST-tagged recombinant p27kip1 with protein kinase cdk2. The phosphorylated, azide-modified protein substrate can be labeled with alkynes of biotin or fluorescent dyes using Cu(I)-catalyzed click chemistry or DBCO-containing biotin or fluorescent dyes using Cu(I)-free click chemistry.
Packaging: 1 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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