L-Pyroglutamic acid
ALDRICH/83160 - ≥99.0% (T)
Synonym: (S)-(−)-2-Pyrrolidone-5-carboxylic acid; (S)
CAS Number: 98-79-3
Empirical Formula (Hill Notation): C5H7NO3
Molecular Weight: 129.11
EC Number: 202-700-3
MDL Number: MFCD00005272
Linear Formula: C5H7NO3
Product Type: Chemical
| application(s) | peptide synthesis |
| assay | ≥99.0% (T) |
| form | solid |
| ign. residue | ≤0.05% |
| InChI | 1S/C5H7NO3/c7-4-2-1-3(6-4 |
| InChI key | ODHCTXKNWHHXJC-VKHMYHEASA |
| mp | 155-162 °C |
| 160-163 °C (lit.) | |
| optical activity | [α]20/D −10.5±1°, c = 5% in H2O |
| optical purity | enantiomeric ratio: ≥99:1 (GC) |
| Quality Level | 200  |
| reaction suitability | reaction type: solution phase peptide synthesis |
| SMILES string | OC(=O)[C@@H]1CCC(=O)N1 |
| Application: | • Nonproteinogenic amino acids such as (3S,4R)-3,4-dimethyl- • Chiral N-heterocyclic carbenes (NHCs) as catalysts for the asymmetric dimerization of alkylarylketenes to give the corresponding α-quaternary β-alkylidenyl-β-lactones. It is also used in the total synthesis of (−)-stemoamide and celogentin C. |
| Packaging: | 25, 100, 500 g in poly bottle |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Purity | ≥99.0% (T) |
| mp | 155-162 °C; 160-163 °C (lit.) |
| UNSPSC | 12352209 |