Friedelin
ALDRICH/855022 - technical grade
Synonym: (4β,5β,8α,9β,10α,13α,14β)-5,9,13-Trimethyl-24,25,26-trinoroleanan-3-one; DA-
CAS Number: 559-74-0
Empirical Formula (Hill Notation): C30H50O
Molecular Weight: 426.72
EC Number: 209-205-1
MDL Number: MFCD00017296
Linear Formula: C30H50O
Product Type: Chemical
| form | solid |
| functional group | ketone |
| grade | technical grade |
| InChI | 1S/C30H50O/c1-20-21(31)9- |
| InChI key | OFMXGFHWLZPCFL-SVRPQWSVSA |
| mp | 262-265 °C (lit.) |
| Quality Level | 100 ![]() |
| SMILES string | C[C@H]1C(=O)CC[C@@H]2[C@] |
| Application: | Friedelin can be used as a starting material in the synthesis of: • Friedel-3-enol acetate, friedel-2-oxo-3-enol acetate, friedel-2-ene derivatives and friedelin ketoxime. • Oxygenated friedelin derivatives as potent DNA topoisomerase IIα inhibitors. • Its 1,4-pyrazine derivatives as potent antimicrobial agents. |
| General description: | Friedelin, a pentacyclic triterpene, is found in several plants like Cissus quadrangularis, Celastrus vulcanicola, Terminalia avicennioides, and Alangium salvifolium. It is known to act as a histamine H1 receptor (H1R) antagonist, anti-microbial, anti-HIV, and anti-cancer agent. |
| Packaging: | 1 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 262-265 °C (lit.) |
| UNSPSC | 12352115 |

