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Friedelin

ALDRICH/855022 - technical grade

Synonym: (4β,5β,8α,9β,10α,13α,14β)-5,9,13-Trimethyl-24,25,26-trinoroleanan-3-one; DA-friedooleanan-3-one; Friedelan-3-one

CAS Number: 559-74-0
Empirical Formula (Hill Notation): C30H50O
Molecular Weight: 426.72
EC Number: 209-205-1
MDL Number: MFCD00017296
Linear Formula: C30H50O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-855022-1G 1 g
$428.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 855022-1G

 

form solid
grade technical grade
InChI 1S/C30H50O/c1-20-21(31)9-10-22-27(20,5)12-11-23-28(22,6)16-18-30(8)24-19-25(2,3)13-14-26(24,4)15-17-29(23,30)7/h20,22-24H,9-19H2,1-8H3/t20-,22+,23-,24+,26+,27+,28-,29+,30-/m0/s1
InChI key OFMXGFHWLZPCFL-SVRPQWSVSA-N
mp 262-265 °C (lit.)
SMILES string C[C@H]1C(=O)CC[C@@H]2[C@]1(C)CC[C@H]3[C@@]2(C)CC[C@@]4(C)[C@@H]5CC(C)(C)CC[C@]5(C)CC[C@]34C
Application: Friedelin can be used as a starting material in the synthesis of:
• Friedel-3-enol acetate, friedel-2-oxo-3-enol acetate, friedel-2-ene derivatives and friedelin ketoxime.
• Oxygenated friedelin derivatives as potent DNA topoisomerase IIα inhibitors.
• Its 1,4-pyrazine derivatives as potent antimicrobial agents.

General description: Friedelin, a pentacyclic triterpene, is found in several plants like Cissus quadrangularis, Celastrus vulcanicola, Terminalia avicennioides, and Alangium salvifolium. It is known to act as a histamine H1 receptor (H1R) antagonist, anti-microbial, anti-HIV, and anti-cancer agent.
Packaging: 1 g in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
mp 262-265 °C (lit.)
UNSPSC 12352115

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