(+)-Biotin 4-nitrophenyl ester
ALDRICH/861650 - 98%
Synonym: 4-Nitrophenyl (+)-biotinate; d-Biotin p-nitrophenyl ester; BNP
CAS Number: 33755-53-2
Empirical Formula (Hill Notation): C16H19N3O5S
Molecular Weight: 365.40
MDL Number: MFCD15141972
Linear Formula: C16H19N3O5S
Product Type: Chemical
assay | 98% |
form | powder |
InChI | 1S/C16H19N3O5S/c20-14(24- |
InChI key | YUDNXDTXQPYKCA-YDHLFZDLSA |
mp | 163-165 °C (lit.) |
optical activity | [α]25/D +51°, c = 2 in DMF: AcOH (99:1) |
SMILES string | [O-][N+](=O)c1ccc(OC(=O)C |
solubility | methanol: 25 mg/mL, clear, colorless to greenish-yellow |
Application: | (+)-Biotin 4-nitrophenyl ester may be used in the preparation of biotin tagged ARC (adenosine-oligoarginine conjugate) derivative during cellular protein uptake studies. It may also be used to prepare biotinylated quinazoline derivatives, which shows inhibitory activities against VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinase. (+)-Biotin 4-nitrophenyl ester undergoes hydrolysis in the presence of Na[17O]H to form [17O2]biotin, which can be used in solid-state 17O NMR spectroscopic experiments to analyze large protein-ligand complexes. Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002 ) |
Packaging: | 100 mg in glass bottle |
Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | 98% |
mp | 163-165 °C (lit.) |
UNSPSC | 12352108 |