SLAP N-Bn-3Me-Pip Reagent
ALDRICH/900406
Synonym: (S)-N1-Benzyl-N1-
CAS Number: 2168413-62-3
Empirical Formula (Hill Notation): C14H26N2Si
Molecular Weight: 250.46
Linear Formula: C14H26N2Si
Product Type: Chemical
| form | liquid |
| Quality Level | 100  |
| storage temp. | −20°C |
| Application: | Silicon amine protocol (SLAP ) reagents, in conjunction with aldehydes and ketones, form N-unprotected piperazines via photocatalytic cross-coupling with Ir[(ppy)2dtbbpy]PF6 (747769 ). Heteroaromatic, aromatic, and aliphatic aldehydes are well tolerated, as are structurally and stereochemically complex SLAP reagents. This product was introduced in collaboration with the Bode Research Group and provides a tin-free alternative to SnAP (tin amine protocol) reagents for piperazine synthesis. |
| Other Notes: | • Technology Spotlight: SLAP Reagents for Piperazine Synthesis • Silicon Amine Reagents for the Photocatalytic Synthesis of Piperazines from Aldehydes and Ketones  • Lewis Acid Induced Toggle from Ir(II) to Ir(IV) Pathways in Photocatalytic Reactions: Synthesis of Thiomorpholines and Thiazepanes from Aldehydes and SLAP Reagents. • Continuous Flow Synthesis of Morpholines and Oxazepanes with Silicon Amine Protocol (SLAP) Reagents and Lewis Acid Facilitated Photoredox Catalysis |
| Packaging: | 500 mg in amber glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352103 |