(4-(Bromomethyl)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone
ALDRICH/900598 - ≥95%
Synonym: Bromo benzophenone alkyne; Probe building block
CAS Number: 1695554-80-3
Empirical Formula (Hill Notation): C17H13BrO2
Molecular Weight: 329.19
MDL Number: MFCD30737994
Linear Formula: C17H13BrO2
Product Type: Chemical
| assay | ≥95% |
| form | solid |
| InChI key | WZAMAERFZALJSY-UHFFFAOYSA |
| Quality Level | 100  |
| reaction suitability | reaction type: click chemistry |
| SMILES string | O=C(C1=CC=C(OCC#C)C=C1)C2 |
| storage temp. | −20°C |
| Application: | Used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments. |
| Other Notes: | Technology Spotlight: Trifuctional Probe Building Blocks Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase  A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS |
| Packaging: | 100 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |