3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

ALDRICH/900605 - ≥95%

Synonym: Bromo sulfonyl fluoride alkyne; Probe building block

CAS Number: 2088829-12-1
Empirical Formula (Hill Notation): C₁₂H₁₄BrFO₂SSi
Molecular Weight: 349.29
Linear Formula: C₁₂H₁₄BrFO₂SSi
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-900605-100MG	100 mg	$412.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
form	solid
Quality Level	100
reaction suitability	reaction type: click chemistry
storage temp.	−20°C

Application:	3-(Bromomethyl)-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for SuFEx -enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Other Notes:	Technology Spotlight: Trifuctional Probe Building Blocks Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis
Packaging:	100 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95%
Storage Temp.	−20°C
UNSPSC	12352200

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