2,5-Dibromohexanediamide
ALDRICH/900607 - ≥95%
Synonym: 2,5-Dibromoadipamide; DBHDA
CAS Number: 99584-96-0
Empirical Formula (Hill Notation): C6H10Br2N2O2
Molecular Weight: 301.96
MDL Number: MFCD27976335
Linear Formula: C6H10Br2N2O2
Product Type: Chemical
assay | ≥95% |
form | solid |
InChI | 1S/C6H10Br2N2O2/c7-3(5(9) |
InChI key | PLSXNAQEJOGNKQ-UHFFFAOYSA |
Quality Level | 100 |
storage temp. | 2-8°C |
Application: | This compound has been shown to be a useful reagent for the conversion of cysteine to dehydroalanine (DHA) in peptides or proteins. This enables chemical mutagenesis in which DHA can be efficiently reacted with iodide building blocks to add various natural and unnatural side chains on proteins. It was also shown that other modifications could be added through DHA such as phosphorylation, methylation, and glycosylation. In other research it was shown that DHA can be used to make ubiquitin conjugates that have a bond that mimics the native isopeptide bond. |
Packaging: | 250 mg in glass insert |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 |
Precautionary statements | P302 + P352 - P305 + P351 + P338 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |