(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone

ALDRICH/900615 - ≥95%

Synonym: Hydroxyl benzophenone alkyne; Probe building block

CAS Number: 1208395-99-6
Empirical Formula (Hill Notation): C₁₆H₁₂O₃
Molecular Weight: 252.26
MDL Number: MFCD28124082
Linear Formula: C₁₆H₁₂O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-900615-100MG	100 mg	$107.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
form	solid
Quality Level	100
reaction suitability	reaction type: click chemistry
storage temp.	−20°C

Application:	(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Other Notes:	Technology Spotlight: Trifuctional Probe Building Blocks A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS Design, synthesis and biological evaluation of photoaffinity probes of antiangiogenic homoisoflavonoids Clickable Photoaffinity Ligands for Metabotropic Glutamate Receptor 5 Based on Select Acetylenic Negative Allosteric Modulators γ-Secretase Modulator (GSM) Photoaffinity Probes Reveal Distinct Allosteric Binding Sites on Presenilin
Packaging:	100 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95%
Storage Temp.	−20°C
UNSPSC	12352200

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