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2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine

ALDRICH/900683 - 95%

Synonym: Amino diazirine alkyne; Probe building block

CAS Number: 1450752-97-2
Empirical Formula (Hill Notation): C7H11N3
Molecular Weight: 137.18
MDL Number: MFCD29918288
Linear Formula: C7H11N3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-900683-100MG 100 mg
 $717.00
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assay 95%
form liquid
InChI key FMCIBERQJQEYIZ-UHFFFAOYSA-N
Quality Level 100 
SMILES string NCCC1(N=N1)CCC#C
storage temp. −20°C
Application: 2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks  to discover the optimal probe for your chemical biology experiments.
Other Notes:
Technology Spotlight: Trifuctional Probe Building Blocks 

Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling 

"Minimalist" Cyclopropene-Containing Photo-Cross-Linkers Suitable for Live-Cell Imaging and Affinity-Based Protein Labeling 
Packaging: 100 mg in glass bottle
Purity 95%
Storage Temp. −20°C
UNSPSC 12352116

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