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(4-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone HCl salt

ALDRICH/900750 - ≥95%

Synonym: Amino (PEG)3 benzophenone alkyne HCl salt; Probe building block

Empirical Formula (Hill Notation): C22H25NO5 · HCl
Molecular Weight: 419.90
MDL Number: MFCD31537179
Linear Formula: C22H25NO5 · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-900750-100MG 100 mg
$363.00
1/EA
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assay ≥95%
form powder
InChI key UHKZPTZAXVJWMN-UHFFFAOYSA-N
Quality Level 100 
reaction suitability reaction type: click chemistry
SMILES string [H]Cl.O=C(C1=CC=C(OCC#C)C=C1)C2=CC=C(OCCOCCOCCN)C=C2
storage temp. −20°C
Application: (4-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)phenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone HCl salt is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its PEGylated amine linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks  to discover the optimal probe for your chemical biology experiments.
Other Notes:
Technology Spotlight: Trifuctional Probe Building Blocks 

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS 

Investigating γ-secretase protein interactions in live cells using active site-directed clickable dual-photoaffinity probes 
Packaging: 100 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95%
Storage Temp. −20°C
UNSPSC 12352200

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