SLAP TA
ALDRICH/900755 - 95%
Synonym: 3-
CAS Number: 2093935-86-3
Empirical Formula (Hill Notation): C7H19NSSi
Molecular Weight: 177.38
MDL Number: MFCD31560650
Linear Formula: C7H19NSSi
Product Type: Chemical
| assay | 95% |
| density | 0.90452 |
| form | liquid |
| functional group | amine |
| thioether | |
| InChI | 1S/C7H19NSSi/c1-10(2,3)7- |
| InChI key | CNESDLLESCAVSR-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | [Si](CSCCCN)(C)(C)C |
| storage temp. | 2-8°C |
| Application: | When used with aliphatic or aromatic aldehydes, this silicon amine protocol SLAP reagent enables the photomediated synthesis of thiomorpholines and thiazepanes. For photocatalytic cross-coupling with this SLAP Reagent, Ir[(ppy)2dtbbpy]PF6 (747769 ) is used with a recommended starting combination of Lewis acids Bi(OTf)3 (633305 ) and Cu(OTf)2 (283673 ) prior to subsequent substrate-specific optimization. This product was introduced in collaboration with the Bode Research Group and provides a tin-free alternative to SnAP (tin amine protocol) reagents and is well-suited for scale-up reactions. |
| Other Notes: | • Technology Spotlight: SLAP Reagents for Piperazine Synthesis • Silicon Amine Reagents for the Photocatalytic Synthesis of Piperazines from Aldehydes and Ketones  • Lewis Acid Induced Toggle from Ir(II) to Ir(IV) Pathways in Photocatalytic Reactions: Synthesis of Thiomorpholines and Thiazepanes from Aldehydes and SLAP Reagents. • Continuous Flow Synthesis of Morpholines and Oxazepanes with Silicon Amine Protocol (SLAP) Reagents and Lewis Acid Facilitated Photoredox Catalysis |
| Packaging: | 500 mg in amber glass bottle |
| Symbol |  GHS02,GHS02 |
| Signal word | Warning;Warning |
| Hazard statements | H226 - H226 |
| Precautionary statements | P210 - P210 - P370 + P378 - P370 + P378 |
| RIDADR | UN 1993C 3 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 75.0 °F |
| Flash Point(C) | 23.89 °C |
| Purity | 95% |
| Density | 0.90452 |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352103 |