Berkessel-Katsuki epoxidation catalyst
ALDRICH/900768 - ≥98%
Synonym: Ti-Berkessel-Katsuki ligand complex; Titanium cis-
CAS Number: 2055468-23-8
Empirical Formula (Hill Notation): C64H40F20N4O6Ti2
Molecular Weight: 1436.73
Linear Formula: C64H40F20N4O6Ti2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 900768-100MG.
| assay | ≥98% |
| form | powder or crystals |
| Quality Level | 100  |
| reaction suitability | core: titanium |
| reagent type: catalyst |
| Application: | Developed by Albrecht Berkessel′s lab, this is the first catalyst that allows catalytic enantioselective epoxidation of non-conjugated terminal double bonds with hydrogen peroxide as the oxidant. Eradicating multiple steps and kinetic resolution, this pre-formed chiral ligand-Ti2O2 catalyst complex provides a one-step route to enantiopure epoxides that are important intermediates for synthesis of bioactive compounds. Catalyst is recyclable under some conditions. For best results, pentafluorobenzoic acid P5360 or tetra-n-butylammonium hydrogensulfate 155837  is recommended as a co-catalyst. |
| Other Notes: | Titanium cis-1,2-Diaminocyclohexane Salalen Catalysts of Outstanding Activity and Enantioselectivity for the Asymmetric Epoxidation of Nonconjugated Terminal Olefins with Hydrogen Peroxide |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| UNSPSC | 12161600 |