Berkessel-Katsuki epoxidation catalyst

ALDRICH/900768 - ≥98%

Synonym: Ti-Berkessel-Katsuki ligand complex; Titanium cis-1,2-diaminocyclohexane salalen catalyst

CAS Number: 2055468-23-8
Empirical Formula (Hill Notation): C₆₄H₄₀F₂₀N₄O₆Ti₂
Molecular Weight: 1436.73
Linear Formula: C₆₄H₄₀F₂₀N₄O₆Ti₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-900768-100MG	100 mg	$209.00 1/EAAdd To Favorites	Add To Favorites

assay	≥98%
form	powder or crystals
Quality Level	100
reaction suitability	core: titanium
	reagent type: catalyst

Application:

Developed by Albrecht Berkessel′s lab, this is the first catalyst that allows catalytic enantioselective epoxidation of non-conjugated terminal double bonds with hydrogen peroxide as the oxidant. Eradicating multiple steps and kinetic resolution, this pre-formed chiral ligand-Ti₂O₂ catalyst complex provides a one-step route to enantiopure epoxides that are important intermediates for synthesis of bioactive compounds. Catalyst is recyclable under some conditions. For best results, pentafluorobenzoic acid P5360 External link

or tetra-n-butylammonium hydrogensulfate 155837 External link

is recommended as a co-catalyst.

Other Notes:

Titanium cis-1,2-Diaminocyclohexane Salalen Catalysts of Outstanding Activity and Enantioselectivity for the Asymmetric Epoxidation of Nonconjugated Terminal Olefins with Hydrogen Peroxide External link

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
UNSPSC	12161600