Berkessel ligand
ALDRICH/900770 - 98%
Synonym: 2′,3′,4′,5′,6′-Pentafluoro-3-({(E)-[(1R,2S)-2-{[(2′,3′,4′,5′,6′-pentafluoro-2-hydroxy[1,1′-biphenyl]-3-yl)methyl]amino}cyclohexyl]imino}methyl)[1,1′-biphenyl]-2-ol; cis-
CAS Number: 2055467-90-6
Empirical Formula (Hill Notation): C32H22F10N2O2
Molecular Weight: 656.51
Linear Formula: C32H22F10N2O2
Product Type: Chemical
| assay | 98% |
| form | powder or crystals |
| Quality Level | 100  |
| reaction suitability | reagent type: ligand |
| Application: | Developed by Albrecht Berkessel′s lab, this is the first catalyst system that allows catalytic enantioselective epoxidation of non-conjugated terminal double bonds with hydrogen peroxide as the oxidant. Eradicating multiple steps and kinetic resolution, this chiral ligand, when used with Ti(OiPr)4 provides a one-step route to enantiopure epoxides that are important intermediates for synthesis of bioactive compounds. Catalyst is recyclable under some conditions. For best results, pentafluorobenzoic acid (P5360 ) or tetra-n-butylammonium hydrogensulfate (155837 ) is recommended as a co-catalyst. |
| Other Notes: | Titanium cis-1,2-Diaminocyclohexane Salalen Catalysts of Outstanding Activity and Enantioselectivity for the Asymmetric Epoxidation of Nonconjugated Terminal Olefins with Hydrogen Peroxide  |
| Packaging: | 100 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Purity | 98% |
| UNSPSC | 12161600 |