2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid

ALDRICH/900858 - ≥95%

Synonym: Carboxyl diazirine alkyne; Probe building block

CAS Number: 2187374-12-3
Empirical Formula (Hill Notation): C₁₂H₇F₃N₂O₃
Molecular Weight: 284.19
Linear Formula: C₁₂H₇F₃N₂O₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-900858-25MG	25 mg	$327.00 1/EAAdd To Favorites	Add To Favorites

assay	≥95%
form	powder
Quality Level	100
reaction suitability	reaction type: click chemistry
SMILES string	C#CCOC1=CC(C2(N=N2)C(F)(F)F)=CC=C1C(O)=O
storage temp.	−20°C

Application:

2-(Prop-2-yn-1-yloxy)-4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks External link

to discover the optimal probe for your chemical biology experiments.

Other Notes:

Technology Spotlight: Trifunctional Probe Building Blocks External link

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥95%
Storage Temp.	−20°C
UNSPSC	12352106