Tetrazine-PEG5-NHS ester
ALDRICH/900913 - ≥95%
Synonym: Tz-PEG5-NHS
CAS Number: 1682653-80-0
Empirical Formula (Hill Notation): C27H36N6O10
Molecular Weight: 604.61
MDL Number: MFCD28505547
Linear Formula: C27H36N6O10
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 900913-50MG.
| assay | ≥95% |
| form | powder or crystals |
| functional group | NHS ester |
| Quality Level | 100  |
| reaction suitability | reaction type: click chemistry |
| reagent type: linker | |
| SMILES string | O=C(NCC1=CC=C(C2=NN=CN=N2 |
| storage temp. | −20°C |
| Application: | Tetrazine-PEG5-NHS ester (Tz-PEG5-NHS) can be used in click chemistry applications such as the preparation of chitosan-polyacrylamide microspheres utilizing selective tetrazine-trans-cyclooctene (Tz-TCO) ligation and the construction of copper-64 radiolabeled antibody by the click reaction. |
| General description: | Tetrazine-PEG5-NHS ester has an N-hydroxysuccinimide (NHS) ester that can be reacted with primary amines and tetrazine, which is reactive to trans-cyclooctenes. Hydrogen substituted tetrazines demonstrate exceptionally fast kinetics, generally at least 10-fold faster compared to methyl substituted tetrazines. The aqueous solubility of this reagent is substantially enhanced by a hydrophilic polyethylene glycol (PEG) spacer arm. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% |
| Storage Temp. | −20°C |
| UNSPSC | 12352108 |