N-Azidoacetylmannosamine-tetraacylated

ALDRICH/900917 - 95%

Synonym: Ac₄ManNAz

CAS Number: 361154-30-5
Empirical Formula (Hill Notation): C₁₆H₂₂N₄O₁₀
Molecular Weight: 430.37
MDL Number: MFCD26961126
Linear Formula: C₁₆H₂₂N₄O₁₀
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-900917-50MG	50 mg	$413.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	95%
form	powder or crystals
InChI	1S/C16H22N4O10/c1-7(21)26-6-11-14(27-8(2)22)15(28-9(3)23)13(16(30-11)29-10(4)24)19-12(25)5-18-20-17/h11,13-16H,5-6H2,1-4H3,(H,19,25)/t11-,13+,14-,15-,16?/m1/s1
InChI key	HGMISDAXLUIXKM-LIADDWGISA-N
Quality Level	100
reaction suitability	reaction type: click chemistry
SMILES string	[N+](=[N-])=NCC(=O)N[C@H]1[C@H]([C@@H]([C@H](OC1OC(=O)C)COC(=O)C)OC(=O)C)OC(=O)C
storage temp.	−20°C

Application:	N-Azidoacetylmannosamine-tetraacylated (Ac₄ManNAz) is an azide-containing metabolic glycoprotein labeling reagent that can be incorporated into the sialic acid biosynthesis pathway. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.
Application:	Tetraacylated N-azidoacetylmannosamine is generally used in click chemistry applications in bioconjugate chemistry.
Packaging:	50 mg in glass insert

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	95%
Storage Temp.	−20°C
UNSPSC	12352116

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