Ephos
ALDRICH/901215 - ≥95%
Synonym: Dicyclohexyl(3-
CAS Number: 2118959-55-8
Empirical Formula (Hill Notation): C36H55OP
Molecular Weight: 534.80
MDL Number: MFCD31619192
Linear Formula: C36H55OP
Product Type: Chemical
| assay | ≥95% |
| form | powder or crystals |
| functional group | phosphine |
| InChI | 1S/C36H55OP/c1-24(2)28-22 |
| InChI key | FDAKNRLXSJBEFL-UHFFFAOYSA |
| mp | 161-162 °C |
| Quality Level | 100 ![]() |
| reaction suitability | reaction type: Buchwald-Hartwig Cross Coupling Reaction |
| reaction type: Heck Reaction | |
| reaction type: Hiyama Coupling | |
| reaction type: Negishi Coupling | |
| reaction type: Sonogashira Coupling | |
| reaction type: Stille Coupling | |
| reaction type: Suzuki-Miyaura Coupling | |
| reagent type: catalyst reaction type: Cross Couplings |
|
| reagent type: ligand | |
| SMILES string | P(C4CCCCC4)(C3CCCCC3)c1c( |
| Application: | Buchwald ligand for Pd-catalyzed C–N cross-coupling between primary amines and arylhalides to form 2-arylaminooxazoles. Catalyst system was reported with NaOPh (CDS001581 ). |
| Application: | Ephos can be used as a ligand in the palladium-catalyzed synthesis of 4-arylaminothiazoles and 2-arylaminooxazoles. |
| Other Notes: | Mechanistic Insight Leads to a Ligand That Facilitates the Pd-Catalyzed Formation of 2-(Hetero)Arylaminooxazol![]() |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% |
| mp | 161-162 °C |
| UNSPSC | 12352128 |

