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Polyester bis-MPA dendron

ALDRICH/901376 - no. Surface Groups 8, 8 acetylene, 1 NHBoc (core), generation 3

Synonym: PFd-G3-BOCNH-Acetylene; bis-MPA dendron

Empirical Formula (Hill Notation): C107H135NO53
Molecular Weight: 2283.19
Linear Formula: C107H135NO53
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-901376-100MG 100 mg
 $632.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 901376-100MG.

 

color white to off-white
form solid
mol wt generation 3
no. Surface Groups 8
Quality Level 100 
storage temp. −20°C
Application: Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. These alkyne-functionalized dendrimers can be readily functionalized using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC), strain-promoted alkyne-azide cycloaddition (SPAAC), or thiol-yne click reactions. Additionally, the amine-functionalized core can be readily used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications.
General description: • Polymer architecture: Dendron
• Generation: 3
• Core functional group: Boc-protected amine
• End Group Functionality: Alkyne
• No. Surface Groups: 8
• Calculated Mol. Wt.: 2283.21 g/mol
• Boc : tert-Butyloxycarbonyl
• bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid
General description: Polyester bis-MPA dendron (8 acetylene, 1 NHBoc (core), generation 3), a high generation dendron, is synthesized by using anhydride activated bis-MPA monomers via divergent growth. It has a large and exact number of reactive groups and has dual functionalization capacity that makes it useful as a high-value scaffold.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12162002

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