Polyester bis-MPA dendron

ALDRICH/901376 - no. Surface Groups 8, 8 acetylene, 1 NHBoc (core), generation 3

Synonym: PFd-G3-BOCNH-Acetylene; bis-MPA dendron

Empirical Formula (Hill Notation): C₁₀₇H₁₃₅NO₅₃
Molecular Weight: 2283.19
Linear Formula: C₁₀₇H₁₃₅NO₅₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-901376-100MG	100 mg	$692.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

color	white to off-white
form	solid
mol wt	generation 3
no. Surface Groups	8
Quality Level	100
storage temp.	−20°C

Application:	Bis-MPA (or 2,2-Bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. These alkyne-functionalized dendrimers can be readily functionalized using either copper(I)-catalysed alkyne-azide cycloaddition (CuAAC), strain-promoted alkyne-azide cycloaddition (SPAAC), or thiol-yne click reactions. Additionally, the amine-functionalized core can be readily used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds to yield highly functionalized materials for a variety of biomedical applications.
General description:	• Polymer architecture: Dendron • Generation: 3 • Core functional group: Boc-protected amine • End Group Functionality: Alkyne • No. Surface Groups: 8 • Calculated Mol. Wt.: 2283.21 g/mol • Boc : tert-Butyloxycarbonyl • bis-MPA : 2,2-Bis(hydroxymethyl)propionic acid
General description:	Polyester bis-MPA dendron (8 acetylene, 1 NHBoc (core), generation 3), a high generation dendron, is synthesized by using anhydride activated bis-MPA monomers via divergent growth. It has a large and exact number of reactive groups and has dual functionalization capacity that makes it useful as a high-value scaffold.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	−20°C
UNSPSC	12162002

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