N-Methylated pomalidomide

ALDRICH/901494 - ≥98%

Synonym: 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; E3 Ligase ligand methylated negative control; Ligand for PROTAC^® research

CAS Number: 1352827-50-9
Empirical Formula (Hill Notation): C₁₄H₁₃N₃O₄
Molecular Weight: 287.27
Linear Formula: C₁₄H₁₃N₃O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-901494-25MG	25 mg	$441.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥98%
form	powder or crystals
ligand	N-Methylated Pomalidomide
Quality Level	100
reaction suitability	reagent type: ligand
shipped in	wet ice
SMILES string	O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3N)=O)N(C)C1=O
storage temp.	2-8°C

Application:	N-Methylated pomalidomide is a ligand used as a negative control for pomalidomide (P0018 ) in the recruitment of the Cereblon (CRBN) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.
Legal Information:	PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
Other Notes:	Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation Portal: Building PROTAC^® Degraders for Targeted Protein Degradation Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4 Targeted Protein Degradation by Small Molecules Small-Molecule PROTACS: New Approaches to Protein Degradation

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
Storage Temp.	2-8°C
UNSPSC	12352101

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