N-Methylated pomalidomide

ALDRICH/901494 - ≥98%

Synonym: 4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione; E3 Ligase ligand methylated negative control; Ligand for PROTAC^® research

CAS Number: 1352827-50-9
Empirical Formula (Hill Notation): C₁₄H₁₃N₃O₄
Molecular Weight: 287.27
MDL Number: MFCD31703382
Linear Formula: C₁₄H₁₃N₃O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-901494-25MG	25 mg	$429.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 901494-25MG.

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98%
form	powder or crystals
InChI	1S/C14H13N3O4/c1-16-10(18)6-5-9(13(16)20)17-12(19)7-3-2-4-8(15)11(7)14(17)21/h2-4,9H,5-6,15H2,1H3
InChI key	YSWQOCGODHPKED-UHFFFAOYSA-N
ligand	N-Methylated Pomalidomide
Quality Level	100
reaction suitability	reagent type: ligand
shipped in	wet ice
SMILES string	O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3N)=O)N(C)C1=O
storage temp.	2-8°C

Application:	N-Methylated pomalidomide is a ligand used as a negative control for pomalidomide (P0018 ) in the recruitment of the Cereblon (CRBN) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.
Legal Information:	PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
Other Notes:	Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation Portal: Building PROTAC^® Degraders for Targeted Protein Degradation Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4 Targeted Protein Degradation by Small Molecules Small-Molecule PROTACS: New Approaches to Protein Degradation

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
Storage Temp.	2-8°C
UNSPSC	12352101

To Order From a Quote