Bromo-PEG3-acid
ALDRICH/901568
CAS Number: 782475-35-8
Empirical Formula (Hill Notation): C9H17BrO5
Molecular Weight: 285.13
MDL Number: MFCD22574820
Linear Formula: C9H17BrO5
Product Type: Chemical
| form | liquid |
| functional group | bromo |
| carboxylic acid | |
| reaction suitability | reagent type: linker |
| SMILES string | BrCCOCCOCCOCCC(O)=O |
| storage temp. | −20°C |
| Application: | Bromo-PEG3-acid is a heterobifunctional, PEGylated crosslinker featuring a bromo group at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. Bromo-PEG3-acid can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation  . |
| Application: | This is a crosslinker with a bromo group on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility. |
| Legal Information: | PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Storage Temp. | −20°C |
| UNSPSC | 12352101 |