t-Boc-N-amido-PEG3-CH2CO2H
ALDRICH/901575 - ≥95%
CAS Number: 462100-06-7
Empirical Formula (Hill Notation): C13H25NO7
Molecular Weight: 307.34
MDL Number: MFCD22376773
Linear Formula: C13H25NO7
Product Type: Chemical
assay | ≥95% |
form | liquid |
functional group | amine |
Boc | |
carboxylic acid | |
InChI | 1S/C13H25NO7/c1-13(2,3)21 |
InChI key | FUUVHHQEYXVKFA-UHFFFAOYSA |
reaction suitability | reagent type: linker |
SMILES string | OC(COCCOCCOCCNC(OC(C)(C)C |
storage temp. | −20°C |
Application: | t-Boc-N-amido-PEG3-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG3-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation . |
Application: | This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility. |
Legal Information: | PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Purity | ≥95% |
Storage Temp. | −20°C |
UNSPSC | 51171641 |