t-Boc-N-amido-PEG₃-CH₂CO₂H

ALDRICH/901575 - ≥95%

CAS Number: 462100-06-7
Empirical Formula (Hill Notation): C₁₃H₂₅NO₇
Molecular Weight: 307.34
MDL Number: MFCD22376773
Linear Formula: C₁₃H₂₅NO₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-901575-50MG	50 mg	$76.30 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
form	liquid
functional group	amine
	Boc
	carboxylic acid
InChI	1S/C13H25NO7/c1-13(2,3)21-12(17)10(14)8-19-6-4-18-5-7-20-9-11(15)16/h10H,4-9,14H2,1-3H3,(H,15,16)
InChI key	FUUVHHQEYXVKFA-UHFFFAOYSA-N
reaction suitability	reagent type: linker
SMILES string	OC(COCCOCCOCCNC(OC(C)(C)C)=O)=O
storage temp.	−20°C

Application:	t-Boc-N-amido-PEG₃-CH₂CO₂H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG₃-CH₂CO₂H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^® molecules) for targeted protein degradation .
Application:	This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains three PEG units to help improve solubility.
Legal Information:	PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

Purity	≥95%
Storage Temp.	−20°C
UNSPSC	51171641

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