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t-Boc-N-amido-PEG2-CH2CO2H

ALDRICH/901577 - ≥95%

CAS Number: 108466-89-3
Empirical Formula (Hill Notation): C11H21NO6
Molecular Weight: 263.29
MDL Number: MFCD17019374
Linear Formula: C11H21NO6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-901577-50MG 50 mg
 $36.90
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assay ≥95%
density 1.15 g/cm3 (lit.)
form liquid
functional group amine
  Boc
  carboxylic acid
InChI 1S/C11H21NO6/c1-11(2,3)18-10(15)12-4-5-16-6-7-17-8-9(13)14/h4-8H2,1-3H3,(H,12,15)(H,13,14)
InChI key OMBVJVWVXRNDSL-UHFFFAOYSA-N
reaction suitability reagent type: linker
SMILES string OC(COCCOCCNC(OC(C)(C)C)=O)=O
storage temp. −20°C
Application: t-Boc-N-amido-PEG2-CH2CO2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-N-amido-PEG2-CH2CO2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC® molecules) for targeted protein degradation .
Application: This is a crosslinker with a t-Boc protected amine on one end and a carboxyl group on the other end. The compound contains two PEG units to help improve solubility.
Legal Information: PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥95%
Density 1.15 g/cm3 (lit.)
Storage Temp. −20°C
UNSPSC 51171641

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