Thiol poly(ethylene glycol)-block-poly(lactide-co-glycolide)
ALDRICH/901941 - PEG average Mn 5,000, PLGA average Mn 15,000, lactide:glycolide 50:50
Synonym: Thiol-PEG-b-PLGA; Thiol-PEG-PLGA
Linear Formula: C3H7SO(C2H4O)nC2H4O[(C2H2O2)x(C3H4O2)y]m
Product Type: Chemical
| color | white |
| description | Identity: Conforms to structure |
| feed ratio | lactide:glycolide 50:50 |
| lactide:glycolide 50:50±5 (by NMR) | |
| form | powder |
| mol wt | PEG average Mn 5,000 |
| PEG Mn 4000-6000 g/mol (by NMR) | |
| PLGA average Mn 15,000 | |
| PLGA Mn 13500-16500 g/mol (by NMR) | |
| storage temp. | −20°C |
| Application: | Thiol poly(ethylene glycol)-block-poly(lactide-co-glycolide) is a thiol-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the thiol-functionalization of the PEG block, this material can be used to rapidly covalently conjugate biomolecules, API, or targeting ligands. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anaesthetic agents. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 51171641 |