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N-Hydroxysuccinimide poly(ethylene glycol)-block-poly(lactide-co-glycolide)

ALDRICH/902241 - PEG average Mn 5000, PLGA average Mn 15000, lactide:glycolide 50:50

Synonym: NHS-PEG-b-PLGA; NHS-PEG-PLGA

Linear Formula: C10H14O5NS(C2H4O)nC2H4O[(C2H2O2)x(C3H4O2)y]mH
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-902241-500MG 500 mg
 $364.00
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color white
feed ratio lactide:glycolide 50:50
  lactide:glycolide 50:50±5
form powder
mol wt PEG average Mn 5000
  PEG Mn 4000-6000 g/mol (by NMR)
  PLGA average Mn 15000
  PLGA Mn 13500-16500 g/mol (by NMR)
storage temp. −20°C
suitability conforms to structure for NMR
Application: N-Hydroxysuccinimide poly(ethylene glycol)-block-poly(lactide-co-glycolide) is a N-hydroxysuccinimide (NHS)-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the NHS-functionalization of the PEG block, this material can be used to rapidly covalently conjugate biomolecules, API, or targeting ligands. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anesthetic agents.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. −20°C
UNSPSC 12352111

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