Thiol functionalized gelatin
ALDRICH/904643
Synonym: Functionalized gelatin; Gelatin thiol; Gelatin-SH• Gel-SH; SH functionalized gelatin; Thiol functionalized gelatin; Thiol gelatin; Thiolated gelatin
Product Type: Chemical
| assay | 150-350 μmol/g (Free Thiol Concentration by UVVI, UV-vis) |
| color | white to pale yellow |
| description | NMR: Conforms to structure |
| Thiol content 150-350 μmol/g | |
| form | powder |
| storage temp. | −20°C |
| Application: | Gelatin has received significant attention in the biomedical field due to its inherent bioactivity. Functionalized gelatin can be cross-linked with the formation of covalent bonds into highly crosslinked structures, such as hydrogels. Recent literature suggests that radical-mediated polymerized hydrogels may not be ideal for cell and protein encapsulation due to radical-mediated damage, hindered molecular transport, or altered cell-cell/cell-material interactions. Thiol-modified gelatin can be used to form hydrogels with multifunctional norbornene or allyl crosslinkers via thiol-ene click or Michael-addition reactions. |
| Application: | To improve solubility in water, heat to 40°C and stir for 10-15 minutes. |
| Caution: | Material should be handled under nitrogen - air/oxygen & moisture are to be avoided. |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 150-350 μmol/g (Free Thiol Concentration by UVVI, UV-vis) |
| Storage Temp. | −20°C |
| UNSPSC | 12352105 |