(6-Bromohexyl)triphenylphosphonium bromide
ALDRICH/905267 - ≥95%
Synonym: Bromohexane TPP mitochondrial tag; Mitochondria-
CAS Number: 83152-22-1
Empirical Formula (Hill Notation): C24H27Br2P
Molecular Weight: 506.25
Linear Formula: C24H27Br2P
Product Type: Chemical
assay | ≥95% |
form | solid |
functional group | phosphine |
InChI | 1S/C24H27BrP.BrH/c25-20-1 |
InChI key | RJXLPJGHUJHULP-UHFFFAOYSA |
reaction suitability | reagent type: ligand |
SMILES string | BrCCCCCC[P+](C1=CC=CC=C1) |
storage temp. | 2-8°C |
Application: | Mitochondria perform several functions in the cell, and dysfunction has been implicated in various organ systems and disease states, including neurodegenerative disorders and cancers. The targeting of small molecules to the mitochondria can help to probe and better understand this relationship. This bromohexane triphenylphosphine (TPP) tag is conjugated to small molecules to localize them to the mitochondria in cells where the TPP cations facilitate both cellular uptake and accumulation in the mitochondria. |
Other Notes: | Targeting lipophilic cations to mitochondria Photoswitchable polyfluorophores based on perylenemonoimide-dithien |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥95% |
Storage Temp. | 2-8°C |
UNSPSC | 12352101 |