(6-Aminohexyl)triphenylphosphonium bromide hydrobromide
ALDRICH/905283 - ≥95%
Synonym: Aminohexane TPP mitochondrial tag; Mitochondria-
Empirical Formula (Hill Notation): C24H29BrNP · xHBr
Molecular Weight: 442.37 (free base basis)
Linear Formula: C24H29BrNP · xHBr
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 905283-1G.
| assay | ≥95% |
| form | solid |
| functional group | phosphine |
| reaction suitability | reagent type: ligand |
| storage temp. | 2-8°C |
| Application: | Mitochondria perform several functions in the cell, and dysfunction has been implicated in various organ systems and disease states, including neurodegenerative disorders and cancers. The targeting of small molecules to the mitochondria can help to probe and better understand this relationship. This aminohexane triphenylphosphine (TPP) tag is conjugated to small molecules to localize them to the mitochondria in cells where the TPP cations facilitate both cellular uptake and accumulation in the mitochondria. |
| Other Notes: | Development of organelle-targetable europium complex probes for time-gated luminescence imaging of hypochlorous acid in live cells and animals   Targeting lipophilic cations to mitochondria Photoswitchable polyfluorophores based on perylenemonoimide-dithien |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352101 |