1,2-Dibromoethane-1-sulfonyl fluoride
ALDRICH/906190
Synonym: DESF; SuFEx hub; SuFEx-able plugin
CAS Number: 103020-97-9
Empirical Formula (Hill Notation): C2H3Br2FO2S
Molecular Weight: 269.92
MDL Number: MFCD31615713
Linear Formula: C2H3Br2FO2S
Product Type: Chemical
| form | liquid |
| reaction suitability | reaction type: click chemistry |
| Application: | 1,2-Dibromoethane-1-sulfo ) click reaction. BESF offers similar routes as ethenesulfonyl fluoride (ESF, cat# 746959 ) but with additional reactivity due to the embedded bromo group.Treatment of DESF with triethylamine generates BESF in situ, which has been used to synthesize diverse and unprecented sulfonyl fluorides in good-to-excellent yields. As the resulting molecules possess sulfonyl fluoride handles, further SuFEx reactions are also possible. DESF adds another useful tool for conjugation strategies in chemical biology and organic and polymer synthesis. Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002 ) |
| Other Notes: | 1-Bromoethene-1-sulfonyl fluoride (BESF) is another good connective hub for SuFEx click chemistry  Regioselective Synthesis of Fluorosulfonyl 1,2,3-Triazoles from Bromovinylsulfonyl Fluoride Technology Spotlight: SuFEx: Sulfonyl Fluorides that Participate in the Next Click Reaction |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352101 |