H-L-Photo-Phe-OH
ALDRICH/907340 - ≥98%
Synonym: (S)
CAS Number: 92367-16-3
Empirical Formula (Hill Notation): C11H10F3N3O2
Molecular Weight: 273.21
MDL Number: MFCD30187606
Linear Formula: C11H10F3N3O2
Product Type: Chemical
| application(s) | peptide synthesis |
| assay | ≥98% |
| availability | available only in USA |
| form | powder |
| InChI | 1S/C11H10F3N3O2/c12-11(13 |
| InChI key | HRGXDARRSCSGOG-UHFFFAOYSA |
| reaction suitability | reaction type: solution phase peptide synthesis |
| storage temp. | −20°C |
| Application: | H- amino acid and multifunctional photo-crosslinker. Its incorporation into peptides or small-molecule probes and tools allows for photoaffinity labeling of cellular targets and protein-protein interactions upon UV light (∼360 nm) irradiation to form a covalent bond. This and other multifunctional probe building blocks will continue to accelerate drug discovery research for probing cellular mechanisms, target ID/validation, and understanding traditionally undruggable targets. An Fmoc-protected version is also available as 907294 .Product can be used with our line of photoreactors : Including Penn PhD (Z744035 ) & SynLED 2.0 (Z744080 ) |
| Other Notes: | Genetic Incorporation of a Photo-Crosslinkable Amino Acid Reveals Novel Protein Complexes with GRB2 in Mammalian Cells  Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation A genetically encoded diazirine photo-crosslinker in Escherichia coli Fishing for Drug Targets: A Focus on Diazirine Photoaffinity Probe Synthesis Photo-affinity labeling (PAL) in chemical proteomics: a handy tool to investigate protein-protein interactions (PPIs) |
| Symbol |  GHS02 |
| Signal word | Danger |
| Hazard statements | H242 |
| Precautionary statements | P210 - P234 - P235 - P240 - P370 + P378 - P403 |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| Storage Temp. | −20°C |
| UNSPSC | 12352101 |