4-Methoxybenzoyl chloride
ALDRICH/A88476 - 99%
Synonym: 4-Anisoyl chloride; p-Anisoyl chloride
CAS Number: 100-07-2
Empirical Formula (Hill Notation): C8H7ClO2
Molecular Weight: 170.59
EC Number: 202-816-4
MDL Number: MFCD00000687
Linear Formula: CH3OC6H4COCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A88476-100G.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: A88476-5G.
| assay | 99% |
| bp | 262-263 °C (lit.) |
| density | 1.260 g/mL at 20 °C (lit.) |
| form | liquid |
| InChI | 1S/C8H7ClO2/c1-11-7-4-2-6 |
| InChI key | MXMOTZIXVICDSD-UHFFFAOYSA |
| mp | 22 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | COc1ccc(cc1)C(Cl)=O |
| Application: | • 4-Methoxybenzoyl chloride can be used as radical precursor in visible-light photocatalysis to synthesize various heterocyclic compounds. • It can be used to synthesize acylphosphine ligands for the rhodium-catalyzed hydrosilylation of alkenes. • Incorporation of 4-methoxybenzoyl chloride modified indium tin oxide (ITO) as cathode for the fabrication of organic light-emitting diodes (OLEDs) has been reported. • 1,3 diketones synthesized from 4-methoxybenzoyl chloride can be used in one pot synthesis of various pyrazole derivatives. • It can also be used in the total synthesis of bioactive compounds like echinoside A and salinosporamide A. |
| General description: | 4-Methoxybenzoyl chloride is one of the reactive acylating agents that can react with carboxylic acids, alcohols and amines to yield respective carboxylic anhydrides, esters and amides. 4-methoxybenzoyl chloride reacts with potassium thiocyanate to yield isothiocyanate derivative via nucleophilic addition-elimination mechanism. |
| Packaging: | 5, 25, 100 g in glass bottle |
| Symbol |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338 + P310 |
| Hazard Codes | C |
| Risk Statements | 14-34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 1729 8 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 188.6 °F - closed cup |
| Flash Point(C) | 87 °C - closed cup |
| Supplemental Hazard Statements | EUH014 |
| Purity | 99% |
| bp | 262-263 °C (lit.) |
| mp | 22 °C (lit.) |
| Density | 1.260 g/mL at 20 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352100 |