2-Bromopyridin-3-yl sulfurofluoridate
ALDRICH/ALD00578 - 95%
Empirical Formula (Hill Notation): C5H3BrFNO3S
Molecular Weight: 256.05
Linear Formula: C5H3BrFNO3S
Product Type: Chemical
assay | 95% |
density | 1.8283 g/mL |
form | liquid |
Quality Level | 100 |
refractive index | n |
storage temp. | 2-8°C |
transition temp | flash point >230 °F |
Application: | 2-Bromopyridin-3-yl sulfurofluoridate can be used in the Pd-catalyzed Suzuki-Miyuara cross-coupling reaction. The fluorosulfate functionality was shown by Sharpless and coworkers to have distinct reactivity in comparison to other functional groups used in Suzuki-Miyuara reactions, such as bromides, chlorides and triflates. This inherent property provides a strong potential for selective Suzuki-Miyuara couplings for chemoselective reaction sequences. |
Other Notes: | Chemoselective Synthesis of Polysubstituted Pyridines from Heteroaryl Fluorosulfates |
Other Notes: | Palladium-Catalyzed, Ligand-Free Suzuki Reaction in Water Using Aryl Fluorosulfates |
Packaging: | 500 mg in poly bottle |
Symbol | GHS05 |
Signal word | Danger |
Hazard statements | H314 |
Precautionary statements | P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
RIDADR | UN 3261 8 / PGII |
WGK Germany | WGK 3 |
Purity | 95% |
Density | 1.8283 g/mL |
Refractive Index | n |
Storage Temp. | 2-8°C |
UNSPSC | 12352200 |