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2-Deoxy-D-galactose

ALDRICH/D4407 - 98%

Synonym: 2-Deoxy-D-lyxohexose

CAS Number: 1949-89-9
Empirical Formula (Hill Notation): C6H12O5
Molecular Weight: 164.16
EC Number: 217-765-3
MDL Number: MFCD00014649
Linear Formula: C6H12O5
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-D4407-1G-A 1 g
$102.00
1/EA
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45-D4407-5G-A 5 g
$310.00
1/EA
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This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D4407-5G-A

 

assay 98%
color white to off-white
form powder
InChI 1S/C6H12O5/c7-2-4-6(10)3(8)1-5(9)11-4/h3-10H,1-2H2/t3-,4-,5?,6-/m1/s1
InChI key PMMURAAUARKVCB-DUVQVXGLSA-N
mp 107 - 110 °C ((225 - 230 °F))
  107-110 °C (lit.)
optical activity [α]20/D +59.7°, c = 2 in H2O
Quality Level 200 
SMILES string OC[C@H]1OC(O)C[C@@H](O)[C@H]1O
Application:

  • FUT1-mediated terminal fucosylation acts as a new target to attenuate renal fibrosis.: This research investigates the role of 2-deoxy-D-galactose in modulating terminal fucosylation processes, revealing potential therapeutic pathways for treating renal fibrosis and enhancing the understanding of kidney disease mechanisms (Luo et al., 2023 ).

  • 2-D-gal Targets Terminal Fucosylation to Inhibit T-cell Response in a Mouse Skin Transplant Model.: Highlights the immunomodulatory potential of 2-deoxy-D-galactose in transplant medicine, showing how it can inhibit T-cell responses and contribute to the success of skin grafts, pointing towards new immunosuppressive treatments (Mao et al., 2023 ).

  • Inhibition of Aberrant α(1,2)-Fucosylation at Ocular Surface Ameliorates Dry Eye Disease.: Explores the therapeutic effects of 2-deoxy-D-galactose in treating dry eye disease by modulating specific fucosylation pathways, potentially opening new avenues for ocular surface treatment strategies (Yoon et al., 2021 ).

General description: 2-Deoxy-D-galactose is a glucose analog that shows a wide range of biological activities such as inhibition of glycolysis and thereby tumor growth, interference with the biosynthetic processing of glycoproteins, antiviral activity, and hepatotoxicity. It is being extensively studied as trapping agents for phosphate and uridylate in mammalian cells due to its ability to interfere in the phosphate and nucleotide metabolism.
Other Notes: To gain a comprehensive understanding of our extensive range of Monosaccharides  for your research, we encourage you to visit our Carbohydrates  Category page.
Packaging: 1, 5 g in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 98%
mp 107 - 110 °C ((225 - 230 °F)); 107-110 °C (lit.)
UNSPSC 12352201

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