Diazolidinyl urea

ALDRICH/D5146 - ≥95%

Synonym: 1-[1,3-Bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea; Diazolidinylurea; N-Hydroxymethyl-N-[1,3-di(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-N′-hydroxymethylurea; N-[1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-N,N′-bis(hydroxymethyl)urea

CAS Number: 78491-02-8
Empirical Formula (Hill Notation): C₈H₁₄N₄O₇
Molecular Weight: 278.22
EC Number: 278-928-2
MDL Number: MFCD03547942
Linear Formula: C₈H₁₄N₄O₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-D5146-25G	25 g	$51.90 1/EA	Add To Favorites
45-D5146-250G	250 g	$186.00 1/EA	Add To Favorites

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This image depicts SKU: D5146-25G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥95%
form	powder
InChI	1S/C8H14N4O7/c13-1-9-7(18)10(2-14)5-6(17)12(4-16)8(19)11(5)3-15/h5,13-16H,1-4H2,(H,9,18)
InChI key	SOROIESOUPGGFO-UHFFFAOYSA-N
Quality Level	100
SMILES string	OCNC(=O)N(CO)C1N(CO)C(=O)N(CO)C1=O
storage temp.	2-8°C

Application:	• Impact of cosmetic preservatives on skin cells: A study examined the effects of various cosmetic preservatives, including Diazolidinyl Urea, on healthy human skin cells, highlighting the cellular responses and potential implications for skin health (Głaz et al., 2023 ). • Formaldehyde releasers in personal care: An extensive clinical review discussed allergic contact dermatitis caused by formaldehyde and formaldehyde releasers such as Diazolidinyl Urea, providing insights into allergic reactions and safety concerns in dermatological practice (Goossens and Aerts, 2022 ). • Carcinogenic potential of cosmetic ingredients: Research on potential carcinogens in makeup cosmetics included Diazolidinyl Urea, emphasizing the safety and regulatory aspects concerning its use in cosmetic formulations (Balwierz et al., 2023 ). • Patch testing for allergen sensitivity: A study integrated Diazolidinyl Urea in a patch test series to evaluate skin sensitization and allergic reactions in patients, aiding in the assessment of its allergenic potential (Bizjak et al., 2022 ).
Disclaimer:	The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.
General description:	Diazolidinyl urea is urea derivative that is commonly used as a preservative and antimicrobial agent in cosmetics and personal care products.
Packaging:	25, 250 g in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H319
Precautionary statements	P264 - P280 - P305 + P351 + P338 - P337 + P313
Hazard Codes	Xi
Risk Statements	43
Safety Statements	36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2

Purity	≥95%
Storage Temp.	2-8°C
UNSPSC	12352100

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