trans-4-Hydroxy-L-proline
ALDRICH/H54409 - ≥99%
Synonym: (2S,4R)
CAS Number: 51-35-4
Empirical Formula (Hill Notation): C5H9NO3
Molecular Weight: 131.13
EC Number: 200-091-9
MDL Number: MFCD00064320
Linear Formula: C5H9NO3
Product Type: Chemical
application(s) | peptide synthesis |
assay | ≥99% |
color | white to off-white |
form | crystalline powder |
InChI | 1S/C5H9NO3/c7-3-1-4(5(8)9 |
InChI key | PMMYEEVYMWASQN-DMTCNVIQSA |
mp | 273 °C (dec.) (lit.) |
optical activity | [α]25/D −75.6°, c = 1 in H2O |
Quality Level | 200 ![]() |
reaction suitability | reaction type: solution phase peptide synthesis |
SMILES string | O[C@H]1CN[C@@H](C1)C(O)=O |
Application: | Versatile reagent for the synthesis of neuroexcitatory kainoids and antifungal echinocandins. Also employed in the synthesis of chiral ligands for enantioselective ethylation of aldehydes. |
General description: | Trans-4-hydroxy-L-proline is an isomer of hydroxyproline used as a chiral building block in the production of many pharmaceuticals like neuroexcitatory kainoids. |
Other Notes: | Natural constituent of animal structural proteins such as collagen and elastin. |
Packaging: | 2.5, 10, 25, 100 g in poly bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Purity | ≥99% |
mp | 273 °C (dec.) (lit.) |
UNSPSC | 12352209 |