trans-4-Hydroxy-L-proline

ALDRICH/H54409 - ≥99%

Synonym: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid; Hyp

CAS Number: 51-35-4
Empirical Formula (Hill Notation): C₅H₉NO₃
Molecular Weight: 131.13
EC Number: 200-091-9
MDL Number: MFCD00064320
Linear Formula: C₅H₉NO₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-H54409-2.5G	2.5 g	$40.40 1/EAAdd To Favorites		Add To Favorites
45-H54409-10G	10 g	$65.90 1/EAAdd To Favorites		Add To Favorites
45-H54409-25G	25 g	$87.90 1/EAAdd To Favorites		Add To Favorites
45-H54409-100G	100 g	$231.00 1/EAAdd To Favorites		Add To Favorites

application(s)	peptide synthesis
assay	≥99%
color	white to off-white
form	crystalline powder
InChI	1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
InChI key	PMMYEEVYMWASQN-DMTCNVIQSA-N
mp	273 °C (dec.) (lit.)
optical activity	[α]25/D −75.6°, c = 1 in H₂O
Quality Level	200
reaction suitability	reaction type: solution phase peptide synthesis
SMILES string	O[C@H]1CN[C@@H](C1)C(O)=O

Application:	Versatile reagent for the synthesis of neuroexcitatory kainoids and antifungal echinocandins. Also employed in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.
General description:	Trans-4-hydroxy-L-proline is an isomer of hydroxyproline used as a chiral building block in the production of many pharmaceuticals like neuroexcitatory kainoids.
Other Notes:	Natural constituent of animal structural proteins such as collagen and elastin.
Packaging:	2.5, 10, 25, 100 g in poly bottle