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trans-4-Hydroxy-L-proline

ALDRICH/H54409 - ≥99%

Synonym: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid; Hyp

CAS Number: 51-35-4
Empirical Formula (Hill Notation): C5H9NO3
Molecular Weight: 131.13
EC Number: 200-091-9
MDL Number: MFCD00064320
Linear Formula: C5H9NO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-H54409-2.5G 2.5 g
 $40.40
1/EA		 Add To Favorites
45-H54409-10G 10 g
 $65.90
1/EA		 Add To Favorites
45-H54409-25G 25 g
 $87.90
1/EA		 Add To Favorites
45-H54409-100G 100 g
 $231.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: H54409-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H54409-2.5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: H54409-2.5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: H54409-10G

 

application(s) peptide synthesis
assay ≥99%
color white to off-white
form crystalline powder
InChI 1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3-,4+/m1/s1
InChI key PMMYEEVYMWASQN-DMTCNVIQSA-N
mp 273 °C (dec.) (lit.)
optical activity [α]25/D −75.6°, c = 1 in H2O
reaction suitability reaction type: solution phase peptide synthesis
SMILES string O[C@H]1CN[C@@H](C1)C(O)=O
Application: Versatile reagent for the synthesis of neuroexcitatory kainoids and antifungal echinocandins. Also employed in the synthesis of chiral ligands for enantioselective ethylation of aldehydes.
General description: Trans-4-hydroxy-L-proline is an isomer of hydroxyproline used as a chiral building block in the production of many pharmaceuticals like neuroexcitatory kainoids.
Other Notes: Natural constituent of animal structural proteins such as collagen and elastin.
Packaging: 2.5, 10, 25, 100 g in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Purity ≥99%
mp 273 °C (dec.) (lit.)
UNSPSC 12352209

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