Iodoacetic acid N-hydroxysuccinimide ester
ALDRICH/I9760 - powder
Synonym: N-Hydroxysuccinimide iodoacetate; N-
CAS Number: 39028-27-8
Empirical Formula (Hill Notation): C6H6INO4
Molecular Weight: 283.02
MDL Number: MFCD00058451
Linear Formula: C6H6INO4
Product Type: Chemical
| application(s) | peptide synthesis |
| form | powder |
| functional group | NHS ester |
| InChI | 1S/C6H6INO4/c7-3-6(11)12- |
| InChI key | VRDGQQTWSGDXCU-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| reaction suitability | reagent type: cross-linking reagent |
| SMILES string | O=C(N1OC(CI)=O)CCC1=O |
| solubility | DMF: 50 mg/mL |
| storage temp. | −20°C |
| Application: | A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5) Second coupling specific for molecules containing free sulfydryl by thioether linkage buffered at pH 7.5 (7.0-8.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 2-atom linker. |
| Disclaimer: | The iodoacetyl group is light sensitive. |
| Packaging: | 50, 100 mg in poly bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352005 |


