Iodoacetic acid N-hydroxysuccinimide ester

ALDRICH/I9760 - powder

Synonym: N-Hydroxysuccinimide iodoacetate; N-Iodoacetoxysuccinimide

CAS Number: 39028-27-8
Empirical Formula (Hill Notation): C₆H₆INO₄
Molecular Weight: 283.02
MDL Number: MFCD00058451
Linear Formula: C₆H₆INO₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-I9760-50MG	50 mg	$313.00 1/EAAdd To Favorites		Add To Favorites
45-I9760-100MG	100 mg	$454.00 1/EAAdd To Favorites		Add To Favorites

application(s)	peptide synthesis
form	powder
functional group	NHS ester
InChI	1S/C6H6INO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2
InChI key	VRDGQQTWSGDXCU-UHFFFAOYSA-N
Quality Level	200
reaction suitability	reagent type: cross-linking reagent
SMILES string	O=C(N1OC(CI)=O)CCC1=O
solubility	DMF: 50 mg/mL
storage temp.	−20°C

Application:	A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5) Second coupling specific for molecules containing free sulfydryl by thioether linkage buffered at pH 7.5 (7.0-8.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 2-atom linker.
Caution:	The iodoacetyl group is light sensitive.
Packaging:	50, 100 mg in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable