Iodoacetic acid N-hydroxysuccinimide ester
ALDRICH/I9760 - powder
Synonym: N-Hydroxysuccinimide iodoacetate; N-
CAS Number: 39028-27-8
Empirical Formula (Hill Notation): C6H6INO4
Molecular Weight: 283.02
MDL Number: MFCD00058451
Linear Formula: C6H6INO4
Product Type: Chemical
application(s) | peptide synthesis |
form | powder |
functional group | NHS ester |
InChI | 1S/C6H6INO4/c7-3-6(11)12- |
InChI key | VRDGQQTWSGDXCU-UHFFFAOYSA |
reaction suitability | reagent type: cross-linking reagent |
SMILES string | O=C(N1OC(CI)=O)CCC1=O |
solubility | DMF: 50 mg/mL |
storage temp. | −20°C |
Application: | A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5) Second coupling specific for molecules containing free sulfydryl by thioether linkage buffered at pH 7.5 (7.0-8.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 2-atom linker. |
Caution: | The iodoacetyl group is light sensitive. |
Packaging: | 50, 100 mg in poly bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 12352005 |