KitAlysis™ High-Throughput Miyaura Borylation Reaction Screening Kit-Pack of 2
ALDRICH/KITALYSIS-BOR
Product Type: Chemical
KitAlysis™ C-N High-Throughout Screening Kit: catalysts, stir bars, preweighed bases, substrate vials, and ampules
12 × 2 preweighed catalysts with stir bars and cap mat
Anhydrous, degassed solvents
Internal standard
Provided substrate bottles, preweighed bases, and stir bars
Complete KitAlysis™ Screening Platform (some components sold seperately)
| functional group | phosphine |
| reaction suitability | reaction type: Buchwald-Hartwig Cross Coupling Reaction |
| reaction type: Cross Couplings | |
| reaction type: Heck Reaction | |
| reaction type: Hiyama Coupling | |
| reaction type: Negishi Coupling | |
| reaction type: Sonogashira Coupling | |
| reaction type: Stille Coupling | |
| reaction type: Suzuki-Miyaura Coupling | |
| reagent type: catalyst core: palladium |
| Application: | Screening kit for Miyaura borylation reaction. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks. Step-by-Step Guide for Miyaura Borylation Reaction Screening Kit  Downloadable Experiment excel sheets Each kit contains 2 customizable screening sets that include the following components:• 6 x 4 pre-weighed catalysts in glass vials loaded with stir bars and topped with cap mat. • 4 x 4 mL reaction vials with pre-weighed KOAc • Bis(pinacolato)diboron (473294 ), tetrahydroxydiboron (754242 ), and pinacol (221171 )• 1 (2 mL) ampule each of toluene, THF, n-butanol, DMA, MeOH, MeCN, ethylene glycol and DIPEA. • 1 NEW KitAlysis 24-Well Reaction Block Replacement Film. • 4 stir bars for substrate stock solution vials. • 1 internal standard. Monitor reaction progress via TLC-MS by following this protocol Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately). |
| Features and Benefits: | • Designed and tested by synthetic chemists. • Easily run 24-microscale reactions in parallel. • 10 μmol reactions with 1 μmol catalyst, 3 equiv. base, 0.1 M concentration. • Customizable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks. |
| Legal Information: | KitAlysis is a trademark of Sigma-Aldrich Co. LLC |
| Symbol |      GHS02,GHS05,GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H225 - H301 + H311 + H331 - H315 - H318 - H335 - H336 - H351 - H360D - H370 - H373 - H410 |
| Precautionary statements | P210 - P273 - P280 - P301 + P310 - P303 + P361 + P353 - P305 + P351 + P338 |
| RIDADR | UN 3316 9 |
| WGK Germany | WGK 3 |
| Flash Point(F) | 1.4 °F |
| Flash Point(C) | -17 °C |
| Supplemental Hazard Statements | EUH019 |
| UNSPSC | 12352300 |
| Components | P(Cy3) Pd G3, 97%; Potassium acetate, anhydrous, free-flowing, Redi-Dri™, ACS reagent, ≥99.0%; XPhos Pd G4, 95%; SPhos Pd G4; RuPhos Pd G4; DTBPF-Pd-G3; cataCXium Pd G4; Toluene, anhydrous, ZerO2®, 99.8%; Ethylene glycol, anhydrous, ZerO2®, 99.8%; N,N-Dimethylacetamide, anhydrous, ZerO2®, 99.8%; Tetrahydrofuran, anhydrous, inhibitor-free, ZerO2®, ≥99.9%; 1-Butanol, anhydrous, ZerO2®, 99.8%; Methanol, anhydrous, ZerO2®, 99.8%; Acetonitrile, anhydrous, ZerO2®, 99.8%; N,N-Diisopropylethylamine, purified by redistillation, ZerO2®, 99.5%; Pinacol, 98%; Bis(pinacolato)diboron, 99%; Tetrahydroxydiboron, 95%; Biphenyl, ReagentPlus®, 99.5%; Spinbar® magnetic stirring fleas, red, L 10 mm, diam. 3 mm; KitAlysis™ 24-well reaction block replacement film |